Oxycodone is considered as a semi-synthetic, morphine-like opioid alkaloid with analgesic activity. It inhibits the release of vasopressin, somatostatin, insulin, and glucagon.
In addition, oxycodone closes N-type voltage-gated calcium channels and opens G-protein-coupled inwardly rectifying potassium channels resulting in hyperpolarization and reduction of neuronal excitability.
This drug is indicated for the treatment of diarrhoea, pulmonary oedema and for the relief of moderate to moderately severe pain.
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